CURRENT COLLABORATIONS
Success with Therapies Research Consortium (STRC)
Formed in 2014, the STRC facilitates the clinical study of interventions to improve day-to-day adherence and cystic fibrosis disease self-management to optimize health outcomes and quality of life and aims to test interventions that are effective, practical, measurable, scalable, and sustainable. I am the Principal Statistician with the STRC Data Management Core (PI: Kristin Riekert) at the Johns Hopkins Adherence Research Center which is responsible for biostatistics and clinical data management for STRC studies.
Motivational interviewing and air cleaners for smokers with COPD (MOVE COPD)
MOVE COPD is a multi-component environmental intervention to improve the health of active smokers with COPD from indoor air pollution reduction. The environmental intervention will target indoor particulate matter, secondhand smoke and nitrous oxide reduction and will evaluate whether this intervention 1) improves respiratory morbidity (i.e., symptoms, quality of life, lung function and exacerbation risk) and 2) intermediate outcome measures (i.e., markers of airway and systemic inflammation and oxidative stress) in smokers with COPD. Results from this study will inform clinical practice guidelines and health care policies aimed at reducing COPD morbidity and may have broader implications for indoor environmental recommendations for smokers with chronic disease.
The home environment and re-hospitalization in COPD study (HEAR COPD)
HEAR COPD is a longitudinal study of individuals with COPD recruited during hospitalization for an exacerbation. This study will evaluate whether in-home air pollution, including ultrafine and fine particulate matter and nitrogen dioxide as well as allergen sensitization exposure is associated with heightened risk of re-hospitalization for COPD exacerbation. These findings will contribute to our understanding of the contribution of indoor air pollution and allergen sensitization exposure to re-hospitalizations in this high-risk population recently hospitalized for exacerbation and provide information to design interventions to modify the home environment post-hospital discharge with the ultimate goal of improving outcomes in COPD.
PDTree: An EMS triage tool for Pediatric Destination Decision Making (pdtree.org)
Regionalized health systems require prehospital triage to match patient needs with facility capabilities; however, EMS protocols lack guidance for EMS transport direction for ill or injured children. With designation of pediatric specialty centers, it is essential that triage tools are developed to guide which children should be preferentially transported to designated pediatric centers. The goals of this project are to: 1) develop the Pediatric Decision Tree (PDTree), a triage tool to guide EMS transport destination choice for ill and injured patients; 2) measure impact of the PDTree in pilot test use by EMS agencies; and 3) disseminate the PDTree and enable adaptation and adoption by EMS agencies throughout the US.
Formed in 2014, the STRC facilitates the clinical study of interventions to improve day-to-day adherence and cystic fibrosis disease self-management to optimize health outcomes and quality of life and aims to test interventions that are effective, practical, measurable, scalable, and sustainable. I am the Principal Statistician with the STRC Data Management Core (PI: Kristin Riekert) at the Johns Hopkins Adherence Research Center which is responsible for biostatistics and clinical data management for STRC studies.
Motivational interviewing and air cleaners for smokers with COPD (MOVE COPD)
MOVE COPD is a multi-component environmental intervention to improve the health of active smokers with COPD from indoor air pollution reduction. The environmental intervention will target indoor particulate matter, secondhand smoke and nitrous oxide reduction and will evaluate whether this intervention 1) improves respiratory morbidity (i.e., symptoms, quality of life, lung function and exacerbation risk) and 2) intermediate outcome measures (i.e., markers of airway and systemic inflammation and oxidative stress) in smokers with COPD. Results from this study will inform clinical practice guidelines and health care policies aimed at reducing COPD morbidity and may have broader implications for indoor environmental recommendations for smokers with chronic disease.
The home environment and re-hospitalization in COPD study (HEAR COPD)
HEAR COPD is a longitudinal study of individuals with COPD recruited during hospitalization for an exacerbation. This study will evaluate whether in-home air pollution, including ultrafine and fine particulate matter and nitrogen dioxide as well as allergen sensitization exposure is associated with heightened risk of re-hospitalization for COPD exacerbation. These findings will contribute to our understanding of the contribution of indoor air pollution and allergen sensitization exposure to re-hospitalizations in this high-risk population recently hospitalized for exacerbation and provide information to design interventions to modify the home environment post-hospital discharge with the ultimate goal of improving outcomes in COPD.
PDTree: An EMS triage tool for Pediatric Destination Decision Making (pdtree.org)
Regionalized health systems require prehospital triage to match patient needs with facility capabilities; however, EMS protocols lack guidance for EMS transport direction for ill or injured children. With designation of pediatric specialty centers, it is essential that triage tools are developed to guide which children should be preferentially transported to designated pediatric centers. The goals of this project are to: 1) develop the Pediatric Decision Tree (PDTree), a triage tool to guide EMS transport destination choice for ill and injured patients; 2) measure impact of the PDTree in pilot test use by EMS agencies; and 3) disseminate the PDTree and enable adaptation and adoption by EMS agencies throughout the US.